At a Glance
| 4-HO-DET | 1,3-Butanediol | |
|---|---|---|
| Class | Psychedelic | Psychedelic |
| Common Dose (oral) | 20–30 mg | — |
| Total Duration | 3.3–5.3 hrs | — |
| Routes | oral | oralsublingual |
Dosage
oral
| Level | 4-HO-DET | 1,3-Butanediol |
|---|---|---|
| Threshold | 5 mg | — mg |
| Light | 10–15 mg | — mg |
| Common | 20–30 mg | — mg |
| Strong | 30–45 mg | — mg |
| Heavy | 45 mg | — mg |
Only in 1,3-Butanediol
sublingual
| Level | Dose |
|---|
Duration
oral
4-HO-DET
oral
Total: 5 hrs – 7 hrsPeak
Offset
Afterglow
Onset20 min – 45 min
Come Up30 min – 1 hrs
Peak2.5 hrs – 3.5 hrs
Effects
Shared Effects5
Safety
Interaction: 4-HO-DET + 1,3-Butanediol
Low Risk & Synergy
Cross-tolerance exists; effects compound
4-HO-DET — Dangerous Interactions
No dangerous interactions recorded.
1,3-Butanediol — Dangerous Interactions
No dangerous interactions recorded.
Frequently Asked Questions
What is the difference between 4-HO-DET and 1,3-Butanediol?
4-HO-DET is classified as a Psychedelic (Substituted tryptamines) while 1,3-Butanediol is classified as a Psychedelic (Substituted tryptamines). They share 5 effects in common, with 46 effects unique to 4-HO-DET and 8 unique to 1,3-Butanediol.
Is it safe to combine 4-HO-DET and 1,3-Butanediol?
The interaction between 4-HO-DET and 1,3-Butanediol is classified as "Low Risk & Synergy". Cross-tolerance exists; effects compound Always research interactions thoroughly before combining any substances.
Which is stronger, 4-HO-DET or 1,3-Butanediol?
Both substances have different dose profiles and pharmacological mechanisms. Comparing "strength" directly is misleading — each has unique effects, durations, and safety considerations.