At a Glance
Dosage
oral
| Level | DOI | 3C-E |
|---|---|---|
| Threshold | 0.5 mg | 20 mg |
| Light | 0.5–1 mg | 30–40 mg |
| Common | 1–2 mg | 40–60 mg |
| Strong | 2–3 mg | 60–80 mg |
| Heavy | 3 mg | 80 mg |
Only in 3C-E
insufflated
| Level | Dose |
|---|---|
| Threshold | 15 mg |
Duration
oral
DOI
oral
Total: 16 hrs – 24 hrsOnset
Come Up
Onset1 hrs – 2 hrs
Come Up1.5 hrs – 3 hrs
3C-E
oral
Total: 10 hrs – 16 hrsPeak
Offset
Effects
Safety
Interaction: DOI + 3C-E
No direct interaction data available between these substances. This does not mean the combination is safe.
DOI — Dangerous Interactions
No dangerous interactions recorded.
3C-E — Dangerous Interactions
No dangerous interactions recorded.
Frequently Asked Questions
What is the difference between DOI and 3C-E?
DOI is classified as a Psychedelic (Substituted amphetamines) while 3C-E is classified as a Psychedelic (Substituted amphetamines). They share 55 effects in common, with 11 effects unique to DOI and 5 unique to 3C-E.
Is it safe to combine DOI and 3C-E?
There is no direct interaction data available for combining DOI and 3C-E. This does not mean the combination is safe. Always exercise caution and research thoroughly.
Which is stronger, DOI or 3C-E?
At common doses via oral, DOI is typically dosed at 1–2 mg while 3C-E is dosed at 40–60 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.