At a Glance
Dosage
oral
| Level | MET | 4-HO-MET |
|---|---|---|
| Threshold | 40 mg | 5 mg |
| Light | 60–120 mg | 5–15 mg |
| Common | 120–150 mg | 15–25 mg |
| Strong | 150–200 mg | 25–45 mg |
| Heavy | 200 mg | 45 mg |
smoked
| Level | MET | 4-HO-MET |
|---|---|---|
| Threshold | 10 mg | 5 mg |
Duration
oral
MET
oral
Total: 4 hrs – 6 hrsAfterglow
Onset1 hrs – 2 hrs
Come Up30 min – 1 hrs
Peak1.5 hrs – 2.5 hrs
Offset
Effects
Safety
Interaction: MET + 4-HO-MET
Low Risk & Synergy
Cross-tolerance exists; effects compound
MET — Dangerous Interactions
No dangerous interactions recorded.
4-HO-MET — Dangerous Interactions
No dangerous interactions recorded.
Frequently Asked Questions
What is the difference between MET and 4-HO-MET?
MET is classified as a Psychedelic (Substituted tryptamines) while 4-HO-MET is classified as a Psychedelic (Substituted tryptamines). They share 47 effects in common, with 20 effects unique to MET and 26 unique to 4-HO-MET.
Is it safe to combine MET and 4-HO-MET?
The interaction between MET and 4-HO-MET is classified as "Low Risk & Synergy". Cross-tolerance exists; effects compound Always research interactions thoroughly before combining any substances.
Which is stronger, MET or 4-HO-MET?
At common doses via oral, MET is typically dosed at 120–150 mg while 4-HO-MET is dosed at 15–25 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.