At a Glance
Dosage
oral
| Level | PCE | 3-HO-PCE |
|---|---|---|
| Threshold | 1 mg | 5 mg |
| Light | 3–5 mg | 5–10 mg |
| Common | 5–10 mg | 10–15 mg |
| Strong | 10–15 mg | 15–25 mg |
| Heavy | — mg | 25 mg |
Only in PCE
insufflated
| Level | Dose |
|---|---|
| Threshold | 1 mg |
Duration
oral
PCE
oral
Total: 4 hrs – 8 hrsAfterglow
Onset30 min – 1.5 hrs
Come Up40 min – 2 hrs
Peak2 hrs – 3 hrs
Offset
Effects
Shared Effects10
Safety
Interaction: PCE + 3-HO-PCE
Caution
Compounding dissociative effects can cause confusion, mania, and loss of motor control
PCE — Dangerous Interactions
Frequently Asked Questions
What is the difference between PCE and 3-HO-PCE?
PCE is classified as a Dissociatives (Arylcyclohexylamines) while 3-HO-PCE is classified as a Dissociatives (Arylcyclohexylamines). They share 10 effects in common, with 4 effects unique to PCE and 38 unique to 3-HO-PCE.
Is it safe to combine PCE and 3-HO-PCE?
The interaction between PCE and 3-HO-PCE is classified as "Caution". Compounding dissociative effects can cause confusion, mania, and loss of motor control Always research interactions thoroughly before combining any substances.
Which is stronger, PCE or 3-HO-PCE?
At common doses via oral, PCE is typically dosed at 5–10 mg while 3-HO-PCE is dosed at 10–15 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.