Question 1

What is the difference between Vitamin B12 and Vitamin D3?

Accepted Answer

Vitamin B12 is classified as a Essential nutrient, Neuroprotective (Corrinoid, Cobalt-containing organometallic compound) while Vitamin D3 is classified as a Essential nutrient, Neuroprotective, Immune modulator (Secosteroid, Steroid hormone precursor). They share 0 effects in common, with 2 effects unique to Vitamin B12 and 2 unique to Vitamin D3.

Question 2

Is it safe to combine Vitamin B12 and Vitamin D3?

Accepted Answer

There is no direct interaction data available for combining Vitamin B12 and Vitamin D3. This does not mean the combination is safe. Always exercise caution and research thoroughly.

Question 3

Which is stronger, Vitamin B12 or Vitamin D3?

Accepted Answer

At common doses via oral, Vitamin B12 is typically dosed at 500–1000 mcg while Vitamin D3 is dosed at 1000–4000 IU. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.

	Vitamin B12	Vitamin D3
Class	Essential nutrient, Neuroprotective	Essential nutrient, Neuroprotective, Immune modulator
Common Dose (oral)	500–1000 mcg	1000–4000 IU
Total Duration	1.2–4.8 hrs	1.2–7.2 hrs
Routes	Oral	Oral

Level	Vitamin B12	Vitamin D3
Threshold	60 mcg	240 IU
Light	100–500 mcg	400–1000 IU
Common	500–1000 mcg	1000–4000 IU
Strong	1000–2500 mcg	4000–10000 IU
Heavy	5000 mcg	— IU

Vitamin B12vsVitamin D3

At a Glance

Dosage

oral

Duration

oral

Oral

Oral

Effects

Unique to Vitamin B122

Unique to Vitamin D32

Safety

Interaction: Vitamin B12 + Vitamin D3

Vitamin B12 — Dangerous Interactions

Vitamin D3 — Dangerous Interactions

Frequently Asked Questions