Before heading out to my New Year's Eve party, I decided to try something I had been curious about for a while. I prepared a 1ml solution of 10mg hexen and 30mg NEP in warm water, which dissolved almost perfectly.
The act of plugging was completely painless. I laid on my side for ten minutes then went about my business getting ready. About twenty to thirty minutes later, I was hit with an intense rush of energy and euphoria comparable to insufflation but lasting much longer. There was a bit more peripheral stimulation than snorted, but that subsided fairly quickly.
I kept insufflating a 30/70 mix of hexen to NEP throughout the evening until around 8am. I did not experience many of the negative effects that others seem to suffer. Sure, the euphoria faded after the initial hours, but I actually enjoyed the scattered, energetic stimulation that remained. It kept me social and dancing all night.
Got home by noon, took a moderate dose of etizolam, and slept like a baby. Woke up feeling almost fine, which surprised me given the length of the session.
The combination works well because hexen provides the initial rush while NEP gives the smoother sustained stimulation. If you can get past the stigma of the route of administration, rectal dosing of this combo is genuinely a superior experience with better bioavailability and less nasal damage.