Complete dosage information for 5-Hydroxytryptophan — threshold, light, common, strong, and heavy dose ranges across 1 route of administration.
Full 5-Hydroxytryptophan profileImportant Safety Notice
Dosage information is for harm reduction purposes only. Individual sensitivity varies greatly. Always start with the lowest effective dose and work your way up slowly. Never eyeball doses — use a milligram scale.
5-HTP overdose from the supplement alone is unlikely to be life-threatening but can cause significant discomfort. Symptoms of taking too much 5-HTP include: - Nausea, vomiting, and diarrhea (from excess gut serotonin) - Stomach cramping - Agitation and restlessness - Rapid heart rate **Combined with serotonergic drugs, serotonin syndrome is the major risk.** Serotonin syndrome is a medical emergency with the following symptoms: - Hyperthermia (dangerously elevated body temperature) - Muscle rigidity and clonus (involuntary rhythmic muscle contractions) - Rapid heart rate and blood pressure swings - Agitation, confusion, delirium - In severe cases: seizures, loss of consciousness, organ failure If serotonin syndrome is suspected, seek emergency medical care immediately. Do not wait to "see if it gets better." Inform medical staff of all substances taken, including supplements.
A common oral dose of 5-Hydroxytryptophan is 100–300 mg.
The threshold dose for 5-Hydroxytryptophan via oral is approximately 25 mg.
5-Hydroxytryptophan typically lasts 4–6 hours via oral.
