Ephylone Dosage Guide

overdose deaths indicate that ephylone is extremely toxic at very high dosages. The DEA claimed approximately 151 ephylone-related deaths occurred in the U.S. between 2014 and 2018. Higher dosages of ephylone have been linked to serotonin syndrome, rhabdomyolysis, kidney injury, acidemia and other life-threatening symptoms. - **Germany:** Ephylone is controlled under Anlage II BtMG (*Narcotics Act, Schedule II*) as of December 21, 2019. It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license. - **Switzerland:** Ephylone can be considered a controlled substance as a defined derivative of Cathinone under Verzeichnis E point 1. It is legal when used for scientific or industrial use. - **United States:** On July 13, 2018, the DEA issued a temporary scheduling order to place ephylone in schedule I of the Controlled Substances Act (CSA). This makes the production, sale, and possession of ephylone illegal. - Responsible use - Entactogens - Stimulants - Cathinones - Methylone - MDPV - Ephylone (Wikipedia) - Ephylone (Isomer Design) - Prosser, J. M., & Nelson, L. S. (2012). The toxicology of bath salts: a review of synthetic cathinones. Journal of Medical Toxicology, 8(1), 33-42. https://doi.org/0.1007/s13181-011-0193-z. - Wood, M. R., Bernal, I., & Lalancette, R. A. (2017). The hydrochloride hydrates of pentylone and dibutylone and the hydrochloride salt of ephylone: the structures of three novel designer cathinones. Structural Chemistry, 28(5), 1369-1376. http://dx.doi.org/10.1007/s11224-017-0951-x - Krotulski, A. J., Papsun, D. M., De Martinis, B. S., Mohr, A. L., & Logan, B. K. (2018). N-Ethyl Pentylone (Ephylone) Intoxications: Quantitative Confirmation and Metabolite Identification in Authentic Human Biological Specimens. Journal of Analytical Toxicology. https://doi.org/10.1093/jat/bky025