LSD Dosage Guide

## Can You Overdose on LSD? In the pharmacological sense — taking enough to cause death — an LSD overdose is extraordinarily unlikely. The estimated lethal dose is roughly 14,000 µg (100-140 standard doses), extrapolated from animal studies. There are documented cases of people accidentally ingesting massive amounts and surviving without lasting physical harm. However, "overdose" in practice usually means taking more than you can psychologically handle. Taking 300+ µg without preparation can produce overwhelming intensity — extended panic, dissociation from reality, dangerous behavior, or catatonia. ## Recognizing a Crisis Seek immediate medical attention if someone shows: - **Hyperthermia** (dangerously elevated body temperature) — the most serious physical risk - **Seizures** — rare with genuine LSD but possible with adulterants like NBOMe compounds - **Signs of serotonin syndrome** (if combined with serotonergic drugs): muscle rigidity, rapid temperature rise, confusion - **Complete unresponsiveness** or catatonia - **Self-harm attempts** or expressed suicidal intent ## What to Do For psychological distress: change the environment, provide calm reassurance ("You are safe, you took a drug, this will end"), and stay present. Benzodiazepines (diazepam 10-20 mg) reliably reduce intensity. For medical emergencies: call emergency services immediately. Good Samaritan laws in many jurisdictions protect people who seek help during drug emergencies from prosecution. There is no specific antidote for LSD; treatment is supportive (IV fluids, cooling for hyperthermia, benzodiazepines for agitation). ## After a Difficult Experience Talk through what happened with a trusted person or therapist within the first few days. Avoid additional psychedelic use for an extended period. Monitor for persistent symptoms — anxiety, depersonalization, visual disturbances — and seek professional help if they continue beyond a few weeks.