Complete dosage information for Morphine — threshold, light, common, strong, and heavy dose ranges across 2 routes of administration.
Full Morphine profileImportant Safety Notice
Dosage information is for harm reduction purposes only. Individual sensitivity varies greatly. Always start with the lowest effective dose and work your way up slowly. Never eyeball doses — use a milligram scale.
Morphine overdose follows the same pattern as all opioid overdoses: respiratory depression progressing to respiratory arrest, hypoxia, and death. Risk is increased with concurrent use of other CNS depressants, after periods of reduced tolerance, and in patients with renal impairment (due to accumulation of the active metabolite M6G). Signs of morphine overdose: extremely slow or stopped breathing, pinpoint pupils, unresponsiveness, blue or gray skin, gurgling sounds, and limpness. Call 911 immediately. Administer naloxone if available. Begin rescue breathing or CPR if the person is not breathing. Place in recovery position. Naloxone may need to be readministered as its duration of action may be shorter than morphine's. Good Samaritan laws apply.
A common oral dose of Morphine is 15–20 mg.
The threshold dose for Morphine via oral is approximately 10 mg.
Morphine typically lasts 4–6 hours via oral.
Morphine can be taken via oral, intravenous. Each route has different dosage ranges and onset times.
