Vitamin B3 produces 5 documented subjective effects across 1 categories.
Full Vitamin B3 profileNiacin (B3) at supplemental doses above the flush threshold produces one of the most dramatic and immediately perceptible effects of any vitamin: the niacin flush. Within fifteen to thirty minutes, the skin turns red and hot, beginning in the face and spreading down the chest and arms. There is an intense, prickling warmth that can be uncomfortable or, for some, oddly pleasant. The flush is caused by prostaglandin-mediated vasodilation and is harmless, lasting twenty to sixty minutes. Beyond the flush, niacin supports mood and cognitive function through its role in NAD+ synthesis, but these benefits are gradual and subtle.
Diarrhea is the occurrence of frequent, loose, or watery bowel movements as a side effect of certain psychoactive substances, resulting from either direct GI irritation or pharmacological alterations to gut motility and fluid absorption.
HeadacheA painful sensation of pressure, throbbing, or aching in the head that can range from a dull background discomfort to a debilitating pounding that dominates awareness. Substance-induced headaches may occur during the acute effects, during the comedown, or as a rebound symptom hours to days after use.
NauseaAn uncomfortable sensation of queasiness and stomach discomfort that may or may not lead to vomiting, often occurring during the onset phase of many substances.
Skin flushingVisible reddening of the skin due to vasodilation, most prominent on the face and chest, commonly caused by alcohol and some psychedelics.
VasodilationVasodilation is the relaxation and widening of blood vessels, leading to increased blood flow, reduced blood pressure, and visible effects such as flushing and bloodshot eyes, most commonly associated with cannabinoids, nitrites, and alcohol.
Vitamin B3 can produce 5 physical effects including headache, nausea, skin flushing, vasodilation, and 1 more.