Ibogaine Dosage Guide

## Overdose Information Ibogaine overdose is a **medical emergency** requiring immediate cardiac intervention. Unlike classical psychedelics, where fatal overdose is extraordinarily rare, ibogaine carries genuine risk of death at doses within or near the therapeutic range -- primarily through cardiac mechanisms, not CNS depression. ### Cardiac Emergency The most life-threatening scenario is **QT prolongation leading to torsade de pointes and cardiac arrest**, which can occur 1.5 to 76 hours after ingestion. Warning signs include: - Irregular heartbeat, palpitations, or the heart "skipping" - Sudden lightheadedness, fainting, or loss of consciousness - Chest pain or pressure - Seizure-like episodes (which may be cardiac arrhythmia rather than neurological seizures) **If any of these occur, call emergency services immediately.** Inform responders that ibogaine was ingested and QT prolongation is the primary concern. IV magnesium sulfate is the frontline intervention. Defibrillation may be required. ### Opioid Interaction Overdose Ibogaine dramatically reduces opioid tolerance. People who return to opioid use afterward at their previous dose face extreme risk of **fatal respiratory depression**. This is one of the most common scenarios in ibogaine-associated fatalities. ### Psychological Emergencies Severe psychological distress can include intense panic, psychotic episodes, and dangerous behavior from impaired reality testing combined with severe ataxia. Move the person to a calm environment, speak reassuringly, and do not restrain unless there is immediate danger. Seek emergency attention for psychotic symptoms or self-harm risk. ### When to Seek Emergency Help - Any cardiac distress (irregular heartbeat, fainting, chest pain) - Seizures or loss of consciousness beyond the expected dream-like state - Difficulty breathing - Uncertain substance identity or dose