At a Glance
| Fentanyl | Hydromorphone | |
|---|---|---|
| Class | Opioids | Opioids |
| Common Dose (insufflated) | 25–50 μg | 2–4 mg |
| Total Duration | 0.3–0.5 hrs | 0.6–1.3 hrs |
| Routes | insufflatedsublingualtransdermal |
Fentanyl, a Opioids, and Hydromorphone, a Opioids, are frequently compared by users looking to understand their relative effects, dosage profiles, and safety considerations. Both are classified as Opioidss, meaning they share a common pharmacological foundation. They share 17 documented effects in common, with 12 effects unique to Fentanyl and 0 unique to Hydromorphone. This side-by-side comparison covers dosage, duration, subjective effects, and safety to help you make informed decisions.
| Fentanyl | Hydromorphone | |
|---|---|---|
| Class | Opioids | Opioids |
| Common Dose (insufflated) | 25–50 μg | 2–4 mg |
| Total Duration | 0.3–0.5 hrs | 0.6–1.3 hrs |
| Routes | insufflatedsublingualtransdermal |
insufflatedintravenousoral |
| Effects | 29 documented | 17 documented |
| Level | Fentanyl | Hydromorphone |
|---|---|---|
| Threshold | 5 μg | 1 mg |
| Light | 10–25 μg | 1–2 mg |
| Common | 25–50 μg | 2–4 mg |
| Strong | 50–75 μg | 4–8 mg |
| Heavy | — μg | 8 mg |
| Level | Dose |
|---|---|
| Threshold | 5 μg |
| Light | 10–25 μg |
| Common | 25–50 μg |
| Strong | 50–75 μg |
| Heavy | 75 μg |
| Level | Dose |
|---|---|
| Threshold | 5 μg |
| Light | 12–25 μg |
| Common | 25–50 μg |
| Strong | 50–100 μg |
| Heavy | 100 μg |
| Level | Dose |
|---|---|
| Threshold | 1 mg |
| Light | 1–2 mg |
| Common | 2–4 mg |
| Strong | 4–6 mg |
| Heavy | 6 mg |
| Level | Dose |
|---|---|
| Threshold | 0.5 mg |
| Light | 1–2 mg |
| Common | 2–4 mg |
| Strong | 4–8 mg |
| Heavy | 8 |
Fentanyl
Hydromorphone
No direct interaction data available between these substances. This does not mean the combination is safe.