At a Glance
| Hydromorphone | Methadone | |
|---|---|---|
| Class | Opioids | Opioids |
| Common Dose (oral) | 2–4 mg | 5–15 mg |
| Total Duration | 1.3–2.6 hrs | 6.3–11.5 hrs |
| Routes | insufflatedintravenousoral |
Hydromorphone, a Opioids, and Methadone, a Opioids, are frequently compared by users looking to understand their relative effects, dosage profiles, and safety considerations. Both are classified as Opioidss, meaning they share a common pharmacological foundation. They share 17 documented effects in common, with 0 effects unique to Hydromorphone and 15 unique to Methadone. This side-by-side comparison covers dosage, duration, subjective effects, and safety to help you make informed decisions.
| Hydromorphone | Methadone | |
|---|---|---|
| Class | Opioids | Opioids |
| Common Dose (oral) | 2–4 mg | 5–15 mg |
| Total Duration | 1.3–2.6 hrs | 6.3–11.5 hrs |
| Routes | insufflatedintravenousoral |
oral |
| Effects | 17 documented | 32 documented |
| Level | Hydromorphone | Methadone |
|---|---|---|
| Threshold | 0.5 mg | 1 mg |
| Light | 1–2 mg | 3–5 mg |
| Common | 2–4 mg | 5–15 mg |
| Strong | 4–8 mg | 15–30 mg |
| Heavy | 8 mg | 30 mg |
| Level | Dose |
|---|---|
| Threshold | 1 mg |
| Light | 1–2 mg |
| Common | 2–4 mg |
| Strong | 4–8 mg |
| Heavy | 8 mg |
| Level | Dose |
|---|---|
| Threshold | 1 mg |
| Light | 1–2 mg |
| Common | 2–4 mg |
| Strong | 4–6 mg |
| Heavy | 6 mg |
Hydromorphone
Methadone
No direct interaction data available between these substances. This does not mean the combination is safe.