What is the difference between Amphetamine and Methamphetamine?

Amphetamine is classified as a Stimulants (Substituted phenethylamines) while Methamphetamine is classified as a Stimulants (Amphetamine, Substituted amphetamines). They share 48 effects in common, with 18 effects unique to Amphetamine and 11 unique to Methamphetamine.

Is it safe to combine Amphetamine and Methamphetamine?

There is no direct interaction data available for combining Amphetamine and Methamphetamine. This does not mean the combination is safe. Always exercise caution and research thoroughly.

Which is stronger, Amphetamine or Methamphetamine?

At common doses via oral, Amphetamine is typically dosed at 10–25 mg while Methamphetamine is dosed at 10–25 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.

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Amphetamine vs Methamphetamine — Effects & Dosage Compared — SubstanceWiki

AmphetaminevsMethamphetamine

Amphetamine, a Stimulants, and Methamphetamine, a Stimulants, are frequently compared by users looking to understand their relative effects, dosage profiles, and safety considerations. Both are classified as Stimulantss, meaning they share a common pharmacological foundation. They share 48 documented effects in common, with 18 effects unique to Amphetamine and 11 unique to Methamphetamine. This side-by-side comparison covers dosage, duration, subjective effects, and safety to help you make informed decisions.

At a Glance

	Amphetamine	Methamphetamine
Class	Stimulants	Stimulants
Common Dose (oral)	10–25 mg	10–25 mg
Total Duration	3.5–7 hrs	4.3–8.8 hrs
Routes	oralintravenousinsufflated

Dosage

oral

Level	Amphetamine	Methamphetamine
Threshold	2.5 mg	5 mg
Light	5–10 mg	5–10 mg
Common	10–25 mg	10–25 mg
Strong	25–50 mg	25–50 mg
Heavy	50 mg	50 mg

intravenous

Level	Amphetamine	Methamphetamine
Threshold	4 mg	5 mg
Light	6–15 mg	5–10 mg
Common	15–30 mg	10–30 mg
Strong	30–50 mg	30–40 mg
Heavy	50 mg	40 mg

insufflated

Level	Amphetamine	Methamphetamine
Threshold	4 mg	5 mg
Light	6–15 mg	5–10 mg
Common	15–30 mg	10–30 mg
Strong	30–50 mg	30–60 mg
Heavy	50 mg	60 mg

Only in Methamphetamine

rectal

Level	Dose
Threshold	5 mg
Light	5–10 mg
Common	10–30 mg
Strong	30–40 mg
Heavy	40 mg

smoked

Level	Dose
Threshold	5 mg
Light	5–10 mg
Common	10–20 mg
Strong	20–60 mg
Heavy	60

AmphetaminevsMethamphetamine

At a Glance

Dosage

oral

intravenous

insufflated

Only in Methamphetamine

rectal

smoked

Duration

oral

oral

oral

intravenous

intravenous

insufflated

insufflated

Only in Methamphetamine

rectal

Effects

Shared Effects48

Unique to Amphetamine18

Unique to Methamphetamine11

Safety

Interaction: Amphetamine + Methamphetamine

Amphetamine — Dangerous Interactions

Methamphetamine — Dangerous Interactions

Frequently Asked Questions

intravenous

insufflated

smoked